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Table 1 Geometric means of live female tick counts at the scheduled hours following treatment and further induced infestations

From: Immediate efficacy and persistent speed of kill of a novel oral formulation of afoxolaner (NexGardTM) against induced infestations with Ixodes ricinus ticks

Days of tick count Day 0 Day 7 Day 14 Day 21 Day 28
Hours of tick counts1 12 h 24 h 12 h 24 h 12 h 24 h 12 h 24 h 12 h 24 h
Number of ticks2 14.5 16.4 20.8 24.4 22.4 21.8 19.1 21.2 19.9 19.3
Untreated Control Group
Number of ticks2 1.0 0.0 4.9 0.0 13.0 0.1 12.1 0.7 12.2 1.7
Treated Group (NexGardTM)
% Efficacy 3 93.4** 100.0** 76.6* 100.0** 41.9 99.4** 36.9* 96.6* 38.5 91.2**
  1. 1Hours of tick counts are indicated either post-treatment on D0 or post-infestation on days 7, 14, 21, 28.
  2. 2Geometric means tick counts.
  3. 3Based on Geometric means.
  4. Treated Group differed statistically significantly from the untreated control Group with:
  5. *(p < 0.05).
  6. **(p < 0.01).
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