Skip to main content

Table 2 Kdr and ace-1 genotype and mutation frequency in Anopheles sinensis mosquitoes from Hainan Island, China

From: Insecticide resistance of Anopheles sinensis and An. vagus in Hainan Island, a malaria-endemic area of China

Insecticide

Population

Bioassay*

N

Kdr genotype

L1014F frequency

P

Ace-1 genotype

G119S frequency

P

    

TTG/TTG

TTG/TTT

(%)

 

GGC/GGC

GGC/AGC

AGC/AGC

(%)

 

0.05% Deltamethrin

Sanya

Resistant

20

17

3

7.5

0.041

0

11

9

72.5

1.000

  

Susceptible

47

47

0

0

 

1

26

20

70.2

 
 

Baoting

Resistant

15

13

2

6.7

0.090

2

7

6

63.3

0.435

  

Susceptible

48

48

0

0

 

10

21

17

57.3

 

4% DDT

Sanya

Resistant

21

17

4

9.5

0.027

0

13

8

69.0

1.000

  

Susceptible

38

38

0

0

 

1

20

17

71.1

 
 

Baoting

Resistant

32

27

5

7.8

0.024

7

9

16

64.1

0.238

  

Susceptible

46

46

0

0

 

13

17

16

53.3

 
  1. *“Resistant” refers to the mosquitoes that were alive 24 hours after 60-min exposure to the insecticides in the standard WHO tube bioassay; and “susceptible” refers to the mosquitoes that were knocked down within the 24-hr recovery period. Significant p-values (p < 0.05) are given in bold type.