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Table 1 Mean tick counts and tick-killing efficacy (%) after oral administration of fluralaner to dogs

From: The speed of kill of fluralaner (Bravecto™) against Ixodes ricinus ticks on dogs

Assessment time pointa 4 hours 8 hours 12 hours 24 hours
Week 0 Mean tick countsb (control/treated) [n] 33.0/3.4 30.6/0.6 28.1/0 15.8/0
Efficacy [%] 89.6# 97.9# 100# 100#
Week 4 Mean tick countsb (control/treated) [n] 36.5/24.4 40.5/1.3 36.7/0.1 30.6/0
Efficacy [%] 33.2* 96.8# 99.7# 100#
Week 8 Mean tick countsb (control/treated) [n] 38.6/31.8 31.2/5.2 32.0/0.3 29.8/0.1
Efficacy [%] 17.5 83.5# 99.2# 99.6#
Week 12 Mean tick countsb (control/treated) [n] 37.4/34.5 30.0/16.2 34.3/0.6 32.7/0.6
Efficacy [%] 7.8 45.8§ 98.3# 98.1#
  1. aAssessment for ticks in hours after treatment or re-infestation.
  2. bGeometric mean.
  3. *Log-counts of live ticks from the treated group were significantly different (p < 0.03) from log-counts of the respective untreated control group.
  4. *Log counts of live ticks from the treated group were significantly different (p < 0.004) from log-counts of the respective untreated control group.
  5. #Log counts of live ticks from the treated group were significantly different (p < 0.0001) from log-counts of the respective untreated control group.