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Table 1 Start to kill study: mean flea counts, flea count range and percentage efficacy 0.5, 1, 2, and 4 hours after a single oral administration of fluralaner to dogs

From: Onset of activity of fluralaner (BRAVECTO™) against Ctenocephalides felis on dogs

Time post treatment

0.5 hour

1 hour

2 hours

4 hours

Study Group

Fluralaner

Control

Fluralaner

Control

Fluralaner

Control

Fluralaner

Control

Mean a flea counts (n)

78.71

73.96

78.14

84.89

48.70

76.97

7.38

61.57

Count range (n)

74-86

65-89

47-96

64-97

33-69

61-99

0-80

30-80

Efficacy (%)

0.0%

8.0%

36.7% b

88.0% b

  1. aGeometric mean.
  2. bLog-counts of live fleas from the treated group were significantly different (p ≤ 0.05) from log-counts of the respective untreated control group.