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Figure 6 | Parasites & Vectors

Figure 6

From: Leishmania enriettii: biochemical characterisation of lipophosphoglycans (LPGs) and glycoinositolphospholipids (GIPLs) and infectivity to Cavia porcellus

Figure 6

GIPLs purified from two strains of L. enriettii (L88 and Cobaia) induce translocation of NF-kB through TLRs. CHO cells expressing TLR2 (TLR2+), TLR4 (TLR4+), or neither (TLR2-/TLR4-) were either untreated (black line) or exposed (gray line) to LPS, S. aureus (SA), L. infantum LPG, L. braziliensis LPG, L. enriettii strain L88 LPG (LPG L88), L. enrietti strain Cobaia LPG (LPG Cobaia), L. enriettii strain L88 GIPL (GIPL L88) or L. enriettii strain Cobaia GIPL (GIPL Cobaia), as indicated. CD25 expression was measured by flow cytometry 18 h after stimulation. Percentage = percentage of CD25 expression on stimulated cells minus percentage of CD25 expression on non-stimulated cells.

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Parasites & Vectors

ISSN: 1756-3305

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