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Table 1 Efficacy of a fipronil-permethrin combination (Frontect®) against Ctenocephalides canis flea challenges in dogs

From: Sustained speed of kill and repellency of a novel combination of fipronil and permethrin against Ctenocephalides canis flea infestations in dogs

Counts on dogs at 1 h post-infestation (PI)
Groups   Day 2 Day 7 Day 14 Day 21 Day 28
Treated (6 dogs) GM 2.97 0.98 7.09 23.89 39.08
Control (6 dogs) GM 84.98 88.99 89.12 80.23 88.26
  p value 0.004922 0.004772 0.004998 0.004998 0.01027
  %Efficacy 96.5 98.9 92.0 70.2 55.7
Counts on dogs at 6 h PI
   Day 2 Day 7 Day 14 Day 21 Day 28
Treated GM 0.00 0.00 0.00 0.00 0.74
Control GM 73.22 81.64 81.01 68.10 79.91
  p value 0.002725 0.002778 0.002778 0.002725 0.004698
  %Efficacy 100.0 100.0 100.0 100.0 99.1
Counts on dogs at 24 h PI
Treated GM 0.00 0.00 0.00 0.00 0.00
Control GM 66.76 77.63 73.61 64.32 76.30
  p value 0.002778 0.002725 0.002778 0.002778 0.002778
  %Efficacy 100.0 100.0 100.0 100.0 100.0
  1. GM = geometric mean. Table lines in Bold = Result lines highlighted.