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Figure 4 | Parasites & Vectors

Figure 4

From: The potential impact of moxidectin on onchocerciasis elimination in Africa: an economic evaluation based on the Phase II clinical trial data

Figure 4

The effect of coverage and non-compliance on programme duration under strategies of annual and biannual community-directed treatment with ivermectin (aCDTI, bCDTI) and annual community-directed treatment with moxidectin (aCDTM). Black bars represent the increment in programme duration caused by a decrease in therapeutic coverage from 80% to 60% of the total population. The green, blue and red bars correspond to a pre-control endemicity level of 40%, 60%, and 80% microfilarial prevalence, respectively. aCDTI, bCDTI and aCDTM are indicated by solid, dashed and dotted bars, respectively. Modelling assumptions are as in the legend of Figure 2. *Provisional operational threshold for treatment interruption followed by surveillance (pOTTIS <1.4% microfilarial prevalence) not attained within the 50-year time horizon.

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