Figure 3
From: Identification of candidate mimicry proteins involved in parasite-driven phenotypic changes
More than 200 tapeworm peptides were identified as significant mimicry candidates through in silico pipeline B. Candidate mimicry identification was achieved through protein similarity analyses. Conserved proteins among distantly related species were discarded based on their high raw similarity score against five different control proteomes, while very similar peptides considered as mimicry candidates were kept based on their high raw similarity score against the stickleback (“true host”) or any of the non-host control (D. rerio, T. rubripes, L. oculatus, O. latipes, and X. macalatus). S. solidus shuffled proteins were also analyzed through pipeline B to make sure that no mimicry peptide could be found only by chance, even with “non-functional biological sequences”. ***p < 0.0001.