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Table 1 Top 18 most abundant proteins representing half of the total mass in SWAP

From: What’s in SWAP? Abundance of the principal constituents in a soluble extract of Schistosoma mansoni revealed by shotgun proteomics

Gene DB Accession

Description

Class

# of Peptides

% Coverage

PD Areaa

MW

[kDa]

% total SWAP

Homo sapiens Accession

% Identity

% Cons.

Signal peptide

Smp_024110.1

Enolase

EM

12

33,4

78,766

47,0

6,1

NP_001419.1

75

86

no

Smp_042160.1

Aldolase

EM

11

27,2

66,915

35,4

5,2

NP_005156.1

69

80

no

Smp_161930.1

Actin

CY

7

30,3

62,296

35,5

4,8

gb|AAP37280.1

67

71

no

Smp_056970.1

Glyceraldehyde 3 P dehydrogenase

EM

6

25,7

48,106

36,4

3,7

NP_002037.2

73

82

no

Smp_095360.1

Fatty acid-binding protein, Sm14

ILT

4

39,9

42,434

14,8

3,3

gb|AAB87141.1

47

61

no

Smp_054160.1

Glutathione S-transferase, GST 28

SR

7

42,7

39,378

23,8

3,1

AAA58623.1

30

48

no

Smp_106930.1

Heat shock 70 kDa protein

CH

17

29,7

32,378

69,8

2,5

NP_006588.1

84

92

no

Smp_050390.1

Aldehyde dehydrogenase

EM

11

31,4

32,212

53,7

2,5

gb|AAH01619.1

57

72

no

Smp_009760.1

14-3-3 protein zeta/delta

CH

6

24,6

31,822

28,4

2,5

NP_003397.1

64

74

no

Smp_040130.1

Cyclophilin

CH

1

8,70

30,114

17,6

2,3

AAH05982.1

67

73

no

Smp_034840.1

14-3-3 protein epsilon

CH

11

48,0

24,916

26,0

1,9

NP_006752.1

65

82

no

Smp_086330.1

Calponin

CB

7

44,2

23,786

21,2

1,8

XP_006722711.1

47

64

no

Smp_183710.1

Actin

CY

7

27,7

21,927

41,7

1,7

NP_001092.1

96

99

no

Smp_049550.1

78 kDa glucose regulated protein

CH

15

25,0

20,302

71,2

1,6

NP_005338.1

75

87

yes

Smp_045200.1

Tegument-allergen-like protein Sm22.6

CB

5

25,8

19,594

22,6

1,5

pdb|2PMY|A

29

50

no

Smp_008070.1

Thioredoxin

SR

7

71,7

19,167

11,9

1,5

NP_003320.2

47

61

no

Smp_086530.1

Tegument-allergen-like protein Sm20.8

CB

7

47,0

18,922

20,8

1,5

BAD97069.1

22

49

no

Smp_096760.1

Phosphoglycerate mutase

EM

10

50,0

17,642

28,4

1,4

NP_000281.2

57

71

no

  

Means

8,4

35,2

35,038

33,7

2,7

 

60

72

 
  1. Annotations in italics were added by the authors
  2. EM Energy metabolism, CY Cytoskeletal, ILT Intracellular lipid transport, SR Stress response, CH Chaperone, CB Calcium binding
  3. aThe Proteome Discoverer (PD) units of area under curve were divided by 106 for ease of manipulation