Fig. 1

a Immunohistochemistry anti-BrdU on small intestine tissue sections from control and infected mice and rats 1 h after BrdU intraperitoneal administration (wpi: week post infection). Cell nuclei were stained with DAPI (blue) and BrdU-positive nuclei are pink. Scale bar: 10 μm. b Number of cells per crypt of Lieberkühn and c percentage of BrdU-labeled cells per crypt 1 h after BrdU administration in mice (white bars) and rats (black bars) at different wpi. Results are presented as mean ± standard deviation. Asterisks indicate significant differences with respect to uninfected controls (0 wpi) for each host species (*p < 0.001). Horizontal bars indicate differences between infected animals at different wpi (a: p < 0.05)