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Fig. 5 | Parasites & Vectors

Fig. 5

From: Autophagic digestion of Leishmania major by host macrophages is associated with differential expression of BNIP3, CTSE, and the miRNAs miR-101c, miR-129, and miR-210

Fig. 5

Ultrastructural investigation of parasite-associated localization of MLS with TEM. Methods: BMDM from BALB/c mice were infected with L. m. promastigotes for 24 h and subjected to TEM analyses. Results: MLS were frequently observed (a) in the cytoplasm of BMDM closely associated with intracellular amastigotes, and (c) localized in the cytoplasm of parasites. e Additionally, digested amastigotes with a defective cell membrane and remains of intracellular MLS were found in L. m.-infected BMDM 24 h p.i.. (b, d, f) Schematic illustrations of images (a, c, and e), respectively

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