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Fig. 6 | Parasites & Vectors

Fig. 6

From: Anopheles stephensi p38 MAPK signaling regulates innate immunity and bioenergetics during Plasmodium falciparum infection

Fig. 6

Inhibition of AsP38 MAPK increased parasite-inducible expression of immune genes in the A. stephensi midgut. Graphs represent means ± SEMs of fold change in the expression of selected immune genes in the midgut of mosquitoes fed a blood meal with P. falciparum freeze/thaw parasite products (FTPP) supplemented with 10 μM BIRB796 or an identical FTPP meal supplemented with an equivalent volume of DMSO as a control. Pairwise comparisons of treatments and matched controls were analysed by Student’s t-test; significant and marginally significant p-values are shown, n = 3-5

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