From: Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells
Cmpd. | C [μg/mL] | Proliferation of parasites [%] in mouse splenocytes | ||
---|---|---|---|---|
BALB/c | C57BL/6 | |||
Toxo-positive (N = 10) | Toxo-negative (N = 14) | Toxo-negative (N = 10) | ||
α-ecdysone | 2 | 89.29 ± 5.90 ↓ | 67.77 ± 5.05* ↓ | 89.69 ± 2.54 ↓ |
10 | 91.17 ± 2.89 ↓ 10 % | 75.69 ± 2.34* ↓ 39 % | 99.75 ± 2.57 ↓ 13 % | |
20 | 99.29 ± 4.14 ↓ | 106.63 ± 2.67* ↓ | 102.58 ± 1.85 ↓ | |
20-hydroxy ecdysone | 2 | 88.65 ± 2.55 | 80.81 ± 3.35* | 99.30 ± 2.55 |
20 | 88.82 ± 3.11 | 109.28 ± 2.11* | 103.73 ± 3.94 | |
100 | 90.02 ± 0.52 | 92.05 ± 2.34 | 97.76 ± 1.85 | |
sulfadiazine | 2 | 92.91 ± 5.11 | 78.34 ± 5.14* | 85.79 ± 1.55* |
20 | 94.18 ± 2.35 | 70.87 ± 3.11* | 74.65 ± 2.48* | |
100 | 81.48 ± 1.52 | 65.32 ± 3.09* | 62.31 ± 2.88* | |
ConA | 2.5 | 192.60 ± 9.65* | 151.48 ± 8.97* | 191.62 ± 9.97* |