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Table 2 Regional distribution of pfdhfr mutations

From: Polymorphism in drug resistance genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium falciparum in some states of India

   pfdhfr genotypes
State N N51I C59R S108N I164L
N I N + I C R C + R S N S + N I L I + L
High transmission areas          
 Jharkhand 84 84 - - 8 46 30 3 55 26 76 4 4
 Odisha 70 67 2 1 22 40 8 21 43 6 66 1 3
 Total 154 151 (98.05 %) 2 (1.3 %) 1 (0.65 %) 30 (19.5 %) 86 (55.8 %) 38 (24.7 %) 24 (15.6 %) 98 (63.6 %) 32 (20.8 %) 142 (92.2 %) 5 (3.2 %) 7 (4.5 %)
Low transmission areas          
 Andhra Pradesh 32 32 - - 17 8 7 14 10 8 32 - -
 Uttar Pradesh 31 31 - - 4 23 4 - 31 - 31 - -
 Total 63 63 (100 %) - - 21 (33.3 %) 31 (49.2 %) 11 (17.5 %) 14 22.2 %) 41 (65.08 %) 8 (12.7 %) 63 (100 %) - -