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Table 3 Regional distribution of pfdhps mutations

From: Polymorphism in drug resistance genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium falciparum in some states of India

State

N

pfdhps genotypes

S436A

A437G

K540E

A581G

S

A

S + A

A

G

A + G

K

E

K + E

A

G

A + G

High transmission areas

          

 Jharkhand

84

76

6

2

55

25

4

76

6

2

64

17

3

 Odisha

70

58

10

2

58

11

1

57

10

3

70

-

-

 Total

154

134 (87.0 %)

16 (10.4 %)

4 (2.6 %)

113 (73.4 %)

36 (23.4 %)

5 (3.2 %)

133 (86.4 %)

16 (10.4 %)

5 (3.2 %)

134 (87.0 %)

17 (11.0 %)

3 (1.9 %)

Low transmission areas

          

 Andhra Pradesh

32

32

-

-

32

-

-

32

-

-

32

-

-

 Uttar Pradesh

31

31

-

-

31

-

-

31

-

-

31

-

-

 Total

63

63 (100 %)

-

-

63 (100 %)

-

-

63 (100 %)

-

-

63 (100 %)

-

-