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Table 3 Regional distribution of pfdhps mutations

From: Polymorphism in drug resistance genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium falciparum in some states of India

State N pfdhps genotypes
S436A A437G K540E A581G
S A S + A A G A + G K E K + E A G A + G
High transmission areas           
 Jharkhand 84 76 6 2 55 25 4 76 6 2 64 17 3
 Odisha 70 58 10 2 58 11 1 57 10 3 70 - -
 Total 154 134 (87.0 %) 16 (10.4 %) 4 (2.6 %) 113 (73.4 %) 36 (23.4 %) 5 (3.2 %) 133 (86.4 %) 16 (10.4 %) 5 (3.2 %) 134 (87.0 %) 17 (11.0 %) 3 (1.9 %)
Low transmission areas           
 Andhra Pradesh 32 32 - - 32 - - 32 - - 32 - -
 Uttar Pradesh 31 31 - - 31 - - 31 - - 31 - -
 Total 63 63 (100 %) - - 63 (100 %) - - 63 (100 %) - - 63 (100 %) - -