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Fig. 4 | Parasites & Vectors

Fig. 4

From: Development of a Real-Time Cell Analysing (RTCA) method as a fast and accurate screen for the selection of chikungunya virus replication inhibitors

Fig. 4

The Effect of the Intensified Concentrations of Drug-Induced Cytotoxicity on Vero Cells Evaluated by both RTCA and MTS Assays. a Vero cell profile after 138 h of incubation with increasing concentrations of cisplatin. The black vertical line indicates the normalisation of the CI time point at 26 h subsequent to Vero cells being treated with cisplatin. Coloured curves represent the various concentrations of cisplatin. Each data point signifies the average ± standard deviation and was analysed in triplicate. Blue line: 8 μg/ml cisplatin; Pink line: 6 μg/ml cisplatin; Turquoise line: 4 μg/ml cisplatin; Purple line: 2 μg/ml cisplatin; Grey line: 0.5 μg/ml cisplatin; Green line: negative control (without cisplatin). Each data point signifies the average ± standard deviation and was analysed in triplicate. b Illustration of the curve of cisplatin effects on Vero cells at 48 and 72 h via MTS assay

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