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Table 1 Parameter notation and values used in the compartmental models

From: Quantitative evaluation of the strategy to eliminate human African trypanosomiasis in the Democratic Republic of Congo

Notation

Description

Value

Source

μ H

Natural human mortality rate

5.4795 × 10− 5 days − 1

[45]

B H

Human birth rate

μ H N H

-

σ H

Human incubation rate

0.0833 days − 1

[17]

φ H

Stage 1 to 2 progression rate

0.0019 days − 1

[39, 46]

γ H

Treatment rate from stage 2

0.006 days − 1

Assumed (see text)

 

u, Proportion of passive cases reported, Varies, -

  
 

Frequency of screening

Annual

-

 

Active screen diagnostic algorithm sensitivity

91 %

Averaged from [38]

 

Active screen diagnostic algorithm sensitivity

91 %

Averaged from [38]

 

Active screen diagnostic algorithm specificity

99.9 %

Averaged from [38]

 

Treatment compliance

1

Assumed

η H

Pulsed active screening

  

ω H

Recovery rate

0.006 days − 1

[27]

δ H

Disease induced mortality

0

Assumed

N H

Total human population size

291567

[34, 35]

k 1

Proportion of low-risk, random participation people

Varies

-

k 2

Proportion of low-risk, random participation people

Varies

-

k 3

Proportion of low-risk, random participation people

Varies

-

k 4

Proportion of low-risk, random participation people

Varies

-

m

Relative tsetse density

N V /N H

-

μ V

Tsetse mortality rate

0.03 days − 1

[17]

α

Tsetse bite rate

0.333 days − 1

WHO 2013

σ V

Tsetse incubation rate

0.034 days − 1

[47, 48]

p V

Probability of tsetse infection per single infective bite

Varies

-

p H

Probability of human infection per single infective bite

Varies

-

m eff

Effective tsetse density

= mp H

-

ε

Reduced non-teneral susceptibility factor

Varies

 

f H

Proportion of blood-meals on humans

0.09

[49] (G. fuscipes)

r

Relative bites taken on “high-risk” humans compared to “low-risk”

Varies

-

μ A

Natural reservoir animal mortality rate

0.0014 days − 1

Assumed

B A

Reservoir animal birth rate

μ A N A

-

σ A

Reservoir animal incubation rate

0.0833 days − 1

[17]

f A

Proportion of blood-meals on reservoir animals

Varies

-

N A

Reservoir animal population size

Varies

-

p A

Probability of reservoir animal infection per single infective bite

Varies

-