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Table 4 Mice immunized with rVtp are protected from infection by tick bite only when challenged with Borrelia hermsii producing the same Vtp antigenic type

From: Vaccination with the variable tick protein of the relapsing fever spirochete Borrelia hermsii protects mice from infection by tick-bite

Challenge strain

Vaccine Type

No. Infected / No. Total

B. hermsii DAH

Adjuvant Only

5/5

 

rVtp DAH

0/5*

 

rVtp LAK-3

5/5

B. hermsii LAK-3

Adjuvant Only

5/5

 

rVtp DAH

5/5**

 

rVtp LAK-3

0/5*

  1. *Significantly different, Fisher’s exact test, p = 0.0003
  2. **One mouse infected during second challenge
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Parasites & Vectors

ISSN: 1756-3305

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