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Table 3 Study 1: mean (standard error) (SE) live flea countsa of control, afoxolaner and spinosad group dogs

From: Speed of flea knockdown of spinosad compared to afoxolaner, and of spinosad through 28 days post-treatment in controlled laboratory studies

  Mean Control Afoxolaner Spinosad
Day 0 - 1 hour Geometric 82.5 (0.1) 90.6 (0.1) 85.1 (0.1)
  Arithmetic 83.7 (3.8) 90.6 (3.8) 85.2 (3.8)
Day 0 - 3 hours Geometric 81.8 (0.2) 79.4 (0.2) 38.5 (0.2)b,c
  Arithmetic 82.3 (6.7) 80.2 (6.7) 44.7 (6.7)b,c
Day 7 - 1 hour Geometric 95.3 (0.1) 83.7 (0.1) 75.2 (0.1)d
  Arithmetic 95.5 (4.2) 84.0 (4.2) 76.5 (4.2)d
Day 7 - 3 hours Geometric 89.2 (0.4) 67.4 (0.4) 12.4 (0.4)e,f
  Arithmetic 89.7 (4.9) 67.8 (4.9)e 21.0 (4.9)e,f
  1. aIncludes moribund fleas, counted as live
  2. Treated group different from control: b p ≤ 0.0051; d p ≤ 0.0128; e p = 0.0069
  3. Different from afoxolaner: c p ≤ 0.0065; f p ≤ 0.0054