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Table 4 Study 2: mean (standard error) (SE) live flea countsa of control, afoxolaner and spinosad group dogs

From: Speed of flea knockdown of spinosad compared to afoxolaner, and of spinosad through 28 days post-treatment in controlled laboratory studies

  Mean Control Afoxolaner Spinosad
Day 0 - 1 hour Geometric 81.2 (0.1) 86.0 (0.1) 71.0 (0.1)b
  Arithmetic 81.8 (4.2) 86.3 (4.2) 71.8 (4.2)b
Day 0 - 3 hours Geometric 89.8 (0.5) 66.3 (0.5) 6.4 (0.5)c,d
  Arithmetic 90.0 (7.3) 70.8 (7.3) 16.5 (7.3)c,d
Day 7 - 1 hour Geometric 91.2 (0.1) 88.9 (0.1) 38.1 (0.1)c,d
  Arithmetic 91.5 (4.5) 89.2 (4.5) 41.5 (4.5)c,d
Day 7 - 3 hours Geometric 89.8 (0.6) 69.0 (0.6) 4.8 (0.6)c,d
  Arithmetic 90.0 (5.4) 70.0 (5.4)e 16.2 (5.4)c,d
  1. aIncludes moribund fleas, counted as live
  2. Treated group different from control: c p ≤ 0.0007; e p = 0.0188
  3. Different from afoxolaner: b p ≤ 0.0276; d p ≤ 0.0019