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Table 4 Study 2: mean (standard error) (SE) live flea countsa of control, afoxolaner and spinosad group dogs

From: Speed of flea knockdown of spinosad compared to afoxolaner, and of spinosad through 28 days post-treatment in controlled laboratory studies

 

Mean

Control

Afoxolaner

Spinosad

Day 0 - 1 hour

Geometric

81.2 (0.1)

86.0 (0.1)

71.0 (0.1)b

 

Arithmetic

81.8 (4.2)

86.3 (4.2)

71.8 (4.2)b

Day 0 - 3 hours

Geometric

89.8 (0.5)

66.3 (0.5)

6.4 (0.5)c,d

 

Arithmetic

90.0 (7.3)

70.8 (7.3)

16.5 (7.3)c,d

Day 7 - 1 hour

Geometric

91.2 (0.1)

88.9 (0.1)

38.1 (0.1)c,d

 

Arithmetic

91.5 (4.5)

89.2 (4.5)

41.5 (4.5)c,d

Day 7 - 3 hours

Geometric

89.8 (0.6)

69.0 (0.6)

4.8 (0.6)c,d

 

Arithmetic

90.0 (5.4)

70.0 (5.4)e

16.2 (5.4)c,d

  1. aIncludes moribund fleas, counted as live
  2. Treated group different from control: c p ≤ 0.0007; e p = 0.0188
  3. Different from afoxolaner: b p ≤ 0.0276; d p ≤ 0.0019