Fig. 1From: Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection Arg1 and Nos2 expression profiles in macrophages infected with different L. infantum strains. The expression of Arg1 (a) and Nos2 (b) was measured by qRT-PCR in murine peritoneal macrophages after 16 and 72 h of infection with L. infantum ITMAP-263, IMT-151 or IMT-202 strains. Non-infected macrophages processed at the referred time points were used as control. Each sample was normalized to Hprt gene, calculated by the comparative CT method (2-ΔΔCT) and the ratio between mRNA levels in infected and non-infected cells is depicted. The graph corresponds to one representative experiment out of three. Statistic analysis was performed using one-way ANOVA with Bonferroni post-hoc test. * p < 0.05; ** p < 0.01; *** p < 0.001 relative to non-infected macrophagesBack to article page