Besnoitia besnoiti lytic cycle in vitro and differences in invasion and intracellular proliferation among isolates

Table 1 Besnoitia spp. isolates used in in vitro assays

Isolate	Isolated from^a	Country	Location	Year of isolation	Reference	Passage numbers (after HFF) used in experiments
Bb-Spain1	Brown Swiss cow	Spain	Guadalajara	2005	[39]	6 to 31
Bb-Spain2	Cow	Spain	Huesca	2005	unpublished	6 to 18
Bb-Italy2	Limousin Cow	Italy	Emilia Romagna Appenines	2012	this study	3 to 11
Bb-Evora03^b	Sallers cow	Portugal	Evora	2003	[63]	2 to 14
Bb-Israel	Cow	Israel	Golan Heights	1986	[52]	3 to 18
Bb-Ger1^b	Charolais bull	Germany	Bavaria	2008	[41]	2 to 15
Bb-France	Cow	France	French Pyrenees		[55]	3 to 13
B. tarandi	Reindeer	Finland	ND	2004	[6]	6 to 11

^aAll isolates originate from animals with visible tissue cysts
^bIsolates with a previous passage through interferon-gamma gene knockout (KO) mice
ND: No data available

ISSN: 1756-3305