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Table 3 Influence of the mouse genetic background on cutaneous leishmaniasis outcome

From: Study of Leishmania pathogenesis in mice: experimental considerations

Locus

Phenotype

Species

Reference

Lsh

Resistance/susceptible (liver parasite load)

L. mexicana

[45, 48]

H2r, s, a, k

Lesion resorption

L. major, L. tropica, L. mexicana

[4648]

H2b, d, q

Slow resolution of lesions

L. major, L. tropica, L. mexicana

[46, 48]

Scl1

Lesion healing

L. major

[16]

Scl2

Lesion development

L. mexicana

[16]

Lmr1, 2, 3….

Lesion healing

L. major

[5052]