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Table 1 Oral infection of mice with metacyclic forms of T. cruzi strainsa

From: Host cell invasion and oral infection by Trypanosoma cruzi strains of genetic groups TcI and TcIV from chagasic patients

T. cruzi strain

(origin)

Mouse

Amastigote nests (number of tissue sections)

Stomach (Day 4)

Stomach (Day 30)

Heart (Day 30)

28

(Brazil Amazon)

1

0 (20)

0 (20)

0 (20)

2

0 (20)

60 (20)

0 (21)

3

0 (20)

285 (20)

0 (20)

4

0 (20)

11 (18)

0 (23)

5

0 (20)

NDb

0 (20)

515

(Venezuela)

1

0 (21)

0 (24)

0 (20)

2

0 (19)

0 (13)

0 (25)

3

0 (20)

0 (21)

0 (23)

4

0 (20)

45 (11)

0 (21)

5

0 (20)

5 (21)

0 (24)

588

(Guatemala)

1

0 (09)

31 (19)

10 (21)

2

0 (12)

17 (18)

0 (20)

3

0 (09)

6 (20)

3 (15)

4

0 (12)

87 (19)

0 (19)

5

0 (16)

990 (20)

0 (16)

1522

(Brazil Northeast)

1

0 (16)

0 (17)

0 (20)

2

0 (19)

0 (15)

4 (20)

3

0 (20)

0 (17)

0 (20)

4

0 (21)

0 (20)

6 (20)

5

0 (21)

0 (16)

4 (18)

1434

(Brazil Amazon)

1

5 (40)

0 (18)

0 (20)

2

3 (40)

0 (24)

0 (20)

3

0 (36)

0 (20)

0 (20)

4

0 (35)

0 (20)

0 (21)

5

5 (40)

0 (20)

0 (21)

  1. aMetacyclic forms of the indicated parasite strains were given orally into mice. In one experiment, mice received 5 × 107 parasites and 4 days later the stomach was collected for histological preparations. In another experiment, mice received 1 × 106 parasites and 30 days later, the stomach and the heart were collected for histological preparations
  2. b ND not determined