Table 3 Absolute amounts of sterols of stationary and metacyclic promastigotes of a virulent strain of Leishmania infantum, incubated in the absence or presence of MβCDa
From: Dynamics of sterol synthesis during development of Leishmania spp. parasites to their virulent form
Sterol | Stationary (n = 6) | Metacyclic (n = 6) | MβCD-metacyclic (n = 6) |
|---|---|---|---|
Cholesterol | 448.3 (249.2) | 248.9 (120.8) | 89.0 (40.6)* |
Ergosterol -I | 331.0 (290.5) | 68.4 (13.1) | 40.3 (22.3)* |
Zymosterol | 44.2 (108.2) | 0.0 (0.0) | 0.0 (0.0) |
Ergosta-7,22-dien-3β-ol - I | 81.8 (40.6) | 100.6 (45.8) | 49.3 (17.2)* |
Ergostatetraenol | 0.0 (0.0) | 0.0 (0.0) | 0.0 (0.0) |
Ergosterol - II | 403.6 (437.7) | 35.7 (33.4) | 11.5 (9.3) |
Ergosta-7,22-dien-3β-ol - II | 387.8 (282.1) | 318.9 (137.8) | 81.8 (37.3)** |
Lanosterol | 6.4 (15.7) | 0.0 (0.0) | 0.0 (0.0) |
Stigmasta-7,24(28)-dien-3β-ol | 62.8 (63.6) | 37.8 (19.4) | 17.5 (8.6)* |
Total | 1766.0 (1307.8) | 810.2 (239.2) | 289.5 (120.7)** |