Skip to main content

Table 5 Acaricides with proven preventive efficacy against Babesia spp. transmission by D. reticulatus and R. sanguineus ticks in dogs

From: A review of canine babesiosis: the European perspective

Principle active (Brand name, presentation - company) Percentage of protection of B. canis infection (time period of evaluation) Acaricide efficacy against D. reticulatus in % (time period of evaluation) Reference
Afoxolaner (NexGard®, chewable tablets - MERIAL) 100 (56 days) 99 (4 weeks) [173]
Fipronil + Permethrin (Frontline Tri-Act®, Spot on - MERIAL) 94.3 (4 weeks) 98.3 (28 days) [174]
Fluralaner (Bravecto®, chewable tablets - MSD) 100 (12 weeks) 99.2 (86 days) [175]
Flumethrin + Imidacloprid (Seresto® Collar - BAYER) 100 (4 weeks) 96.0 (48 h), 100 (4 days) [176]
  Percentage of protection of B. vogeli infection (time period of evaluation) Acaricide efficacy against R. sanguineus in % (time period of evaluation)  
Flumethrin + Imidacloprid (Seresto® Collar - BAYER) 100 (1 year) 99.7 (48 h) [177]
Imidacloprid + Permethrin (Advantix®, spot on - BAYER) 88.3–94.4 % (12 months)a 95–100 [178, 179]
  1. aThe molecular diagnosis was Babesia spp. Identification to the species level was not carried out. However, the studies were performed in the south of Italy, so that the species of Babesia infecting dogs was most likely B. vogeli