Fig. 1

Phylogenetic analysis of S. japonicum acetylcholinesterase and functionally characterised acetylcholinesterases from other taxa. Species (Sequence Accession Number) used for the analysis include: Mus musculus (EDL19281), Bos taurus (NP_001069688), Homo sapiens (AAA68151), Tetronarce californica (X03439), Xenopus tropicalis (XP_002931610), Ambigolimax valentianus (BAO00806), Crassostrea gigas (XP_011422197), Caenorhabditis elegans (W09B12.1.1*), Hymenolepis microstoma (HmN_000644400*), Taenia solium (TsM_000001700*), Echinococcus granulosus (EgrG_000732400*), Echinococcus multilocularis (EmuJ_000732400*), Clonorchis sinensis (csin108144*), Opisthorchis viverrini (T265_07137*), Fasciola hepatica (BN1106_s773B000378), Schistosoma. haematobium (AF279462), S. bovis (AF279463), S. mansoni (AF279461). Note: *: Gene ID from WormBase ParaSite web site (http://parasite.wormbase.org/Multi/Tools/Blast)