Immunomodulatory effects of tick saliva on dermal cells exposed to Borrelia burgdorferi, the agent of Lyme disease

Table 5 B. burgdorferi-perturbed genes up-regulated after 2 h of stimulation

Gene	Relative expression	Description
IGHG1	0.07896333	Variable 3–11 (gene/pseudogene); immunoglobulin heavy variable 4–31; immunoglobulin heavy locus
HIF1AN	1.40558447	Hypoxia inducible factor 1, alpha subunit inhibitor
FGFR3	3.37091511	Fibroblast growth factor receptor 3
CD6	2.9080693	CD6 molecule
CD300E	0.65831278	CD300e molecule
CD200	2.10422558	CD200 molecule
GPR89A	1.7942643	G protein-coupled receptor
BAT3	0.09701591	HLA-B associated transcript 3
IL15RA	0.28488171	Interleukin 15 receptor, alpha
NCF1	0.41282425	Neutrophil cytosolic factor 1
MAP3K7IP1	0.13999618	Mitogen-activated protein kinase kinase kinase 7 interacting protein 1
RAB1A	0.68755658	RAB1A, member RAS oncogene family
IL12RB1	0.78907124	Interleukin 12 receptor, beta 1
TNFRSF13B	0.02283238	Tumor necrosis factor receptor superfamily, member 13B
IL1F10	1.59882878	Interleukin 1 family, member 10 (theta)
BAD	0.44343992	BCL2-associated agonist of cell death
RASSF7	1.95038068	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RASGRF1	0.28493451	Ras protein-specific guanine nucleotide-releasing factor 1
CNOT7	0.31888622	CCR4-NOT transcription complex, subunit 7
LTBP1	2.24423737	Latent transforming growth factor beta binding protein 1
CD44	0.61183676	CD44 molecule (Indian blood group)

ISSN: 1756-3305