Skip to main content

Table 2 Acute toxicity of crude green tea (Camellia sinensis) extract on exposure to L3/L4 instars of A. arabiensis and A. gambiae (s.s.) for 24, 48 and 72 h post-exposure. Summary of percentage mean (± SD) mortality rates of five replicates of mosquito larvae exposed to different concentrations of C. sinensis crude leaf extract for different time periods (24, 48 and 72 h). Half maximal lethal concentrations (LC50) for each dose exposure period have been determined at their 95 % confidence intervals. The mosquito larvae exhibited significant susceptibility to the bioactive fraction at P < 0.05

From: Potential of Camellia sinensis proanthocyanidins-rich fraction for controlling malaria mosquito populations through disruption of larval development

  Concentration (ppm) Lethal concentration (ppm)
Time 500 250 100 50 25 Control LC50 95 % CI
An. arabiensis*
 24 h 86 ± 9.62 75 ± 24.75 30 ± 19.69 0 ± 0.00 0 ± 0.00 0 ± 0.00 154.58 152.37–158.22
 48 h 98 ± 4.47 92 ± 5.70 53 ± 20.19 0 ± 0.00 0 ± 0.00 0 ± 0.00 154.58 152.37–158.22
 72 h 100 ± 0.00 95 ± 5.00 60 ± 18.03 0 ± 0.00 0 ± 0.00 0 ± 0.00 154.58 152.37–158.22
An. gambiae (s.s.)*
 24 h 100 ± 0.00 91 ± 9.62 39 ± 6.52 0 ± 0.00 0 ± 0.00 0 ± 0.00 117.15 112.86–127.04
 48 h 100 ± 0.00 98 ± 2.24 62 ± 10.37 0 ± 0.00 0 ± 0.00 0 ± 0.00 87.11 82.57–112.82
 72 h 100 ± 0.00 100 ± 0.00 84 ± 11.94 0 ± 0.00 0 ± 0.00 0 ± 0.00 87.11 82.57–112.82
  1. Data presented as mean ± SD of five replicates
  2. Abbreviations: LC 50 lethal concentration that killed 50 % of test mosquito larvae population, CI confidence interval
  3. *Mean values are not significantly different P ≤ 0.05 (ANOVA)