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Table 4 Predictors of infection with STH overall, Ascaris lumbricoides and hookworm, across pilot study sentinel sites in Burundi from 2007 to 2011 combined with prevalence data obtained by a mapping survey in 2014 from the same schools. Results shown are from binomial mixed models. Age was standardised (mean centred and divided by the estimated standard deviation)

From: The impact of an 8-year mass drug administration programme on prevalence, intensity and co-infections of soil-transmitted helminthiases in Burundi

 

Pooled STH

Ascaris lumbricoides

Hookworm

n = 22,341 observations

pseudo-R 2 MF = 0.057; R 2 marg. = 0.037; R 2 cond. = 0.21

n = 22,347 observations

pseudo-R 2 MF = 0.17; R 2 marg. = 0.028; R 2 cond. = 0.40

n = 22,351 observations

pseudo-R 2 MF = 0.13; R 2 marg. = 0.079; R 2 cond. = 0.48

Fixed effects

Category

Parameter

(SE)

Adjusted odds ratio

(95 % CI)

P

Parameter

(SE)

Adjusted odds ratio

(95 % CI)

P

Parameter

(SE)

Adjusted odds ratio

(95 % CI)

P

(Intercept)

 

-0.90 (0.17)

0.41 (0.29–0.56)

***

-2.5 (0.36)

0.08 (0.04–0.17)

***

-2.20 (0.44)

0.11 (0.05–0.26)

***

Year

2008

-0.90 (0.26)

0.4 (0.24–0.67)

***

-1.05 (0.4)

0.35 (0.16–0.76)

**

-1.29 (0.28)

0.28 (0.16–0.47)

***

 

2009

-0.43 (0.23)

0.65 (0.41–1.01)

ns

-0.24 (0.45)

0.79 (0.33–1.89)

ns

-0.87 (0.35)

0.42 (0.21–0.82)

*

 

2010

-0.90 (0.20)

0.41 (0.27–0.61)

***

-0.84 (0.26)

0.43 (0.26–0.72)

**

-1.36 (0.34)

0.26 (0.13–0.5)

***

 

2011

-1.14 (0.23)

0.32 (0.2–0.5)

***

-0.48 (0.2)

0.62 (0.41–0.92)

*

-2.26 (0.38)

0.10 (0.05–0.22)

***

 

2014

-0.85 (0.25)

0.43 (0.26–0.71)

***

0.05 (0.31)

1.05 (0.57–1.93)

ns

-1.48 (0.5)

0.23 (0.09–0.6)

**

Age

 

-0.07 (0.019)

0.94 (0.9–0.97)

***

-0.12 (0.025)

0.89 (0.85–0.93)

***

0.02 (0.028)

1.02 (0.97–1.08)

ns

Age^2

 

-0.01 (0.017)

0.99 (0.95–1.02)

ns

-0.03 (0.023)

0.97 (0.93–1.01)

ns

-0.02 (0.025)

0.98 (0.94–1.03)

ns

Sex (male)

 

0.09 (0.037)

1.09 (1.01–1.17)

*

0.08 (0.048)

1.08 (0.98–1.19)

ns

0.09 (0.053)

1.09 (0.98–1.21)

ns

Random Effects

 

Variance

SD

 

Variance

SD

 

Variance

SD

 

Pupil (Intercept)

 

0.43

0.66

***

0.56

0.75

***

0.33

0.57

***

School (Intercept)

 

0.31

0.55

 

1.50

1.23

 

2.20

1.50

 

Year 2008

 

0.76

0.87

 

1.60

1.25

 

0.63

0.79

 

Year 2009

 

0.59

0.77

 

2.20

1.48

 

1.3

1.14

 

Year 2010

 

0.46

0.68

 

0.66

0.81

 

1.2

1.10

 

Year 2011

 

0.59

0.77

 

0.36

0.60

 

1.1

1.05

 

Year 2014

 

0.60

0.78

 

0.84

0.92

 

1.8

1.35

 

Random Slope year

   

***

  

***

  

***

  1. Abbreviations: ns not significant (P > 0.05); SD standard deviation; SE standard error
  2. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001