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Table 2 Evaluation of lesion growth for Josefa strain and LV78 strain infections in mice

From: Efficacy of intranasal LaAg vaccine against Leishmania amazonensis infection in partially resistant C57Bl/6 mice

 

Josefa C57Bl/6-UFFa (Fig. 2a)

 

LV78 C57Bl/6-UFFb (Fig. 2a)

DPI

t-value

(df = 8)

P-value

DPI

t-value

(df = 8)

P-value

7

5.668

0.0005

6

23.16

<0.0001

14

5.233

0.0008

14

23.09

<0.0001

28

2.801

0.0232

20

15.83

<0.0001

70

2.561

0.0336

26

14.50

<0.0001

77

3.322

0.0105

34

8.164

<0.0001

85

3.644

0.0065

41

10.70

<0.0001

92

3.845

0.0049

49

2.454

0.0397

100

3.845

0.0049

91

3.274

0.0113

   

105

4.253

0.0028

   

112

4.512

0.0020

   

118

4.712

0.0015

   

125

5.632

0.0005

  1. We evaluated mice (from UFF) infection with L. amazonensis using Josefa strain or LV78 strain. The results of the Student’s t-test for lesion size from different times (days post-infection) with peak of infection are shown; see also Fig. 2
  2. Abbreviations: DPI days post-infection, UFF Universidade Federal Fluminense
  3. aPeak of infection at day 49 post-infection
  4. bPeak of infection at day 55 post-infection