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Table 1 Transmission of CHIKV from mosquitoes to mice

From: Chikungunya virus transmission between Aedes albopictus and laboratory mice

Mice

Confirmed mosquitoes fed

Viraemia day 2 (log10CCID50/ml)

Peak % foot swelling R & L

Mortality; day post-feeding

IgG2c anti-CHIKV response

C57BL/6J

     

1

3

7.5

nd

Alive

+a

2

2

7.5

nd

Alive

+a

3

1

7.5

nd

Alive

+a

IRF3/7-/-

     

1

1

12.5

101 (d 9) 14 (d 13)

13

+b

2

1

10

17 (d 13) 46 (d 13)

14

+b

3

1

10.5

59 (d 7) 70 (d 7)

Alive

+b

  1. Abbreviation: nd not detected, R & L right and left foot
  2. aOD >17-fold higher than background for 1/20 dilutions of sera collected day 21 post-feeding
  3. bOD >10-fold higher than background for 1/20 dilutions of sera collected upon euthanasia or day 21 post-feeding