Fig. 3

BLAST analysis of the Cyclospora apicoplast reference genome with other apicomplexans. Apicoplast genomes from an eimeriid, E. tenella and a sarcocystid, T. gondii (brown and green bars, respectively) and a plasmodiid, P. falciparum 3D7 (violet) are compared with the C. cayetanensis apicoplast (outer circles with purple, blue and maroon bands) using CGview software with its built-in Blast tool with the default e-value cutoff of 0.1. The thickness of the bands indicates sequence similarity. The eimeriid and sarcocystid apicoplasts have higher nucleotide similarity while the Plasmodium apicoplast is least similar of the three recapitulating evolutionary distance between these species. The predicted proteomes of these divergent apicomplexans contain mostly conserved core gene content (Fig. 2a)