Skip to main content

Table 6 ELISA results from the complete 116 sera and two further scarring case-control studies. The three arrayed antigens were tested on the complete set of 116 sera (2006), 231 samples from a previous scarring case-control study in The Gambia (1995) and a subsequent scarring case-control study in The Gambia (2011). CT442 showed no association with the absence of scarring, and CT667/CT706 were not associated with scarring

From: Profiling and validation of individual and patterns of Chlamydia trachomatis-specific antibody responses in trachomatous trichiasis

Antigen

Sera

Healthy median (IQR)

Scarred median (IQR)

P-value

OR (95% CI)

CT442

2006

0.24 (0.19–0.33)

0.27 (0.18–0.33)

0.368

0.33 (0.02–3.36)

1995

0.29 (0.18–0.43)

0.30 (0.15–0.46)

0.990

1.00 (0.46–2.13)

2011

0.31 (0.22–0.38)

0.36 (0.24–0.48)

0.023

36.19 (2.20–1109.21)

CT667

2006

0.04 (0.03–0.06)

0.04 (0.03–0.07)

0.169

2766.28 (0.06–6.20 × 108)

1995

0.14 (0.05–0.23)

0.12 (0.03–0.23)

0.344

0.59 (0.18–1.68)

2011

0.03 (0.02–0.06)

0.03 (0.02–0.07)

0.802

0.23 (2.47 × 10-6–24,634.90)

CT706

2006

0.05 (0.03–0.07)

0.04 (0.03–0.06)

0.289

42.59 (0.07–1.26 × 105)

1995

0.14 (0.06–0.23)

0.12 (0.04–0.23)

0.307

0.58 (0.18–1.57)

2011

0.02 (0.02–0.06)

0.03 (0.02–0.08)

0.940

1.24 (0.005–619.41)