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Table 3 ELISA and MBA results for each antigen in neurocysticercosis patients with two or more viable cysts (n = 77)

From: Comparison of T24H-his, GST-T24H and GST-Ts8B2 recombinant antigens in western blot, ELISA and multiplex bead-based assay for diagnosis of neurocysticercosis

Test

Area

95% CI

SE

P

Cut-off

S (%)

Sp (%)

T24H-his ELISA

0.98

0.971–0.996

0.006

< 0.001

23.3

88.3

96.5

GST-Ts8B2 ELISA

0.97

0.951–0.989

0.010

< 0.001

34.5

75.3

96.5

GST-T24H ELISA

0.99

0.982–0.998

0.004

< 0.001

21.1

88.3

96.5

T24H-his MBA

0.98

0.966–0.994

0.007

< 0.001

9.2

84.4

96.5

GST-Ts8B2 MBA

0.74

0.667–0.819

0.039

< 0.001

250.0

46.8

91.2

GST-T24H MBA

0.99

0.981–0.999

0.005

< 0.001

4.0

96.1

96.5

  1. Abbreviations: Area area under the ROC curve, CI confidence interval, SE standard error, Cut-off serological index value selected as the cut-off for each test, S (%) sensitivity percentage, Sp (%) specificity percentage