From: A high-throughput colorimetric assay for detection of Schistosoma mansoni viability based on the tetrazolium salt XTT
Compound
IC50 (μM)
XTT Assay
Microscopy
Mefloquine
8.9 ± 0.6
10.2 ± 0.2
Ivermectin
2.2 ± 0.1
2.3 ± 0.1
JQ1
21.2 ± 2.9
19.6 ± 0.3
Praziquantel
~ 588a
~ 472a
Curcumin
13.0 ± 5.7
14.7 ± 0.3
Amphotericin
2.4 ± 0.1
0.2 ± 0.04