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Table 1 Impact of mast cell deficiency on B. burgdorferi (s.s.) 297 dissemination

From: Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice

Day/ Organ Joints (%)a Heart (%)a Ear (%)a
C57BL/6 (10 weeks)
 Day 3 (n = 8) 0 0 0
 Day 5 (n = 8) 0 0 0
 Day 7 (n = 5) 60 0 0
 Day 15 (n = 8) 75 0 0
Kit Wsh −/− (10 weeks)
 Day 3 (n = 7) 0 0 0
 Day 5 (n = 10) 10 0 0
 Day 7 (n = 12) 50 0 0
 Day 15 (n = 10) 90 0 10
  1. Wild type or KitWsh −/− mice were infected intradermally with Borrelia burgdorferi 297 strain (103 bacteria/100 μl) by syringe inoculation. The dissemination of Borrelia was determined by in vitro culture and by qPCR performed on the different distant organs: the joint, the heart and the ear
  2. aThe percentage of positive samples to Borrelia is calculated according to 5 mice minimum per group
  3. Abbreviations: n number of mice per group, day day of infection