Fig. 1

Dynamic changes of splenic dendritic cells subsets in mice infected with S. japonicum. The number of CD8α⁺DCs changed consistently with the trend of Th1 response during the infection of S. japonicum. a Percentages of CD11c⁺CD8a⁺ cells analysed by FACS at 0, 3, 6 and 9 weeks post-infection. The upper right quadrant is the proportion of CD8α⁺DCs subsets. b Percentage of CD8α⁺DCs in the spleen. Data are presented as the means ± SEM from six mice in each group (***P < 0.001). Results are representative of two independent experiments. c Percentages of CD11c⁺CD8a⁺ cells analysed by FACS in Batf3 ^−/− mice. The upper right quadrant is the proportion of CD8α⁺DCs subsets