Comparative efficacy of a new spot-on combination product containing selamectin and sarolaner (Stronghold®Plus) versus fluralaner (Bravecto®) against induced infestations with Ixodes ricinus ticks on cats

Table 1 Acaricidal efficacy based on the arithmetic (geometric) mean tick counts for Ixodes ricinus as well as the number of cats with ticks at the different time points after treatment

Study day	Group 1^a		Group 2^b (Selamectin/Sarolaner)			Group 3^c (Fluralaner)
Study day	n	Mean tick count	n	Mean tick count	Percentage efficacy	n	Mean tick count	Percentage efficacy
Day 28	8/8	16.6 (16.3)	1/8	0.4 (0.3)^*	97.6 (98.2)	0/7	0.0 (0.0)^*	100 (100)
Day 56	8/8	17.4 (16.6)	1/8	0.3 (0.1)^*	98.3 (99.4)	4/7	3.0 (1.5)^*	82.8 (91.0)
Day 84	8/8	19.1 (18.4)	1/8	0.3 (0.2)^*	98.4 (98.9)	6/7	6.3 (3.9)^*	67.1 (78.8)
Day 91	8/8	23.6 (23.4)	2/7	1.0 (0.5)^*	95.8 (97.8)	6/7	6.3 (3.0)^*	73.3 (87.2)

^aNegative control
^bCats were treated topically on Days 0, 30 and 60 with selamectin/sarolaner (Stronghold®Plus)
^cCats were treated topically on Day 0 with fluralaner (Bravecto®)
^*Mean tick counts sign (P < 0.05) lower than control group
n number of cats with ticks

ISSN: 1756-3305