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Table 3 Distribution of SNPs in some target genes of antimalarial drugs and immunity

From: Pooled-DNA sequencing identifies genomic regions of selection in Nigerian isolates of Plasmodium falciparum

Gene Name

Chromosome

Position

Number of SNPs

UBP1

1

190,269–210,230

4

LSA3

2

796,752–801,568

6

PFDHR

4

748,088–749,914

13

PFMDR1

5

957,890–962,149

8

PFCRT

7

403,222–406,317

5

PFDHPS

8

548,200–550,616

7

MSP1

9

1,201,812–1,206,974

6

GDV1

9

1,377,953–1,379,752

4

MSP3

10

1,404,195–1,405,259

5

LSA1

10

1,436,316–1,439,804

5

PFMDR5

13

1,598,401–1,601,178

10

  1. Abbreviations: UBP1 ubiquitinating emzyme gene, CRT chloroquine resistant transporter, MDR multidrug resistant transporter, DHFR dihydrofolate reductase, DHPS dihydropteroate synthase, GDV gametocyte development, MSP merozoite surface protein, LSA liver stage antigen
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Parasites & Vectors

ISSN: 1756-3305

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