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Table 7 Results of ANOVA comparisons between groups

From: Synergy between dinotefuran and fipronil against the cat flea (Ctenocephalides felis): improved onset of action and residual speed of kill in adult cats

Variable

Time point

Study day

ANOVA result

Arithmetic mean

Geometric mean

Curative efficacy (Group 1 vs Group 2)

3 h

0

F (1,14) = 118.08, P < 0.0001

F (1,14) = 371.28, P < 0.0001

6 h

F (1,14) = 101.36, P < 0.0001

F (1,14) = 1553.43, P < 0.0001

12 h

F (1,14) = 115.48, P < 0.0001

F (1,14) = 964.38, P < 0.0001

Preventative efficacy (Group 1 vs Group 3)

6 h

7

F (1,14) = 148.72, P < 0.0001

F (1,14) = 279.06, P < 0.0001

14

F (1,14) = 111.47, P < 0.0001

F (1,14) = 269.66, P < 0.0001

21

F (1,14) = 142.48, P < 0.0001

F (1,14) = 128.82, P < 0.0001

28

F (1,14) = 149.25, P < 0.0001

F (1,14) = 44.38, P < 0.0001

35

F (1,14) = 26.42, P = 0.0002

F (1,14) = 13.08, P = 0.0028

42

F (1,14) = 19.45, P = 0.0006

F (1,14) = 9.85, P = 0.0073

48 h

9

F (1,14) = 353.47, P < 0.0001

F (1,14) = 6013.11, P < 0.0001

16

F (1,14) = 236.02, P < 0.0001

F (1,14) = 621.06, P < 0.0001

23

F (1,14) = 109.50, P < 0.0001

F (1,14) = 216.72, P < 0.0001

30

F (1,14) = 75.43, P < 0.0001

F (1,14) = 702.01, P < 0.0001

37

F (1,14) = 49.96, P < 0.0001

F (1,14) = 61.03, P < 0.0001

44

F (1,14) = 109.33, P < 0.0001

F (1,14) = 78.76, P < 0.0001

  1. Abbreviations: ANOVA, analysis of variance; Time point, time in hours after administration of the Investigational Veterinary Product (curative efficacy), or time in hours after flea infestation (preventative efficacy); h, hours