Table 7 Results of ANOVA comparisons between groups

Variable Time point Study day ANOVA result
Arithmetic mean Geometric mean
Curative efficacy (Group 1 vs Group 2) 3 h 0 F (1,14) = 118.08, P < 0.0001 F (1,14) = 371.28, P < 0.0001
6 h F (1,14) = 101.36, P < 0.0001 F (1,14) = 1553.43, P < 0.0001
12 h F (1,14) = 115.48, P < 0.0001 F (1,14) = 964.38, P < 0.0001
Preventative efficacy (Group 1 vs Group 3) 6 h 7 F (1,14) = 148.72, P < 0.0001 F (1,14) = 279.06, P < 0.0001
14 F (1,14) = 111.47, P < 0.0001 F (1,14) = 269.66, P < 0.0001
21 F (1,14) = 142.48, P < 0.0001 F (1,14) = 128.82, P < 0.0001
28 F (1,14) = 149.25, P < 0.0001 F (1,14) = 44.38, P < 0.0001
35 F (1,14) = 26.42, P = 0.0002 F (1,14) = 13.08, P = 0.0028
42 F (1,14) = 19.45, P = 0.0006 F (1,14) = 9.85, P = 0.0073
48 h 9 F (1,14) = 353.47, P < 0.0001 F (1,14) = 6013.11, P < 0.0001
16 F (1,14) = 236.02, P < 0.0001 F (1,14) = 621.06, P < 0.0001
23 F (1,14) = 109.50, P < 0.0001 F (1,14) = 216.72, P < 0.0001
30 F (1,14) = 75.43, P < 0.0001 F (1,14) = 702.01, P < 0.0001
37 F (1,14) = 49.96, P < 0.0001 F (1,14) = 61.03, P < 0.0001
44 F (1,14) = 109.33, P < 0.0001 F (1,14) = 78.76, P < 0.0001
1. Abbreviations: ANOVA, analysis of variance; Time point, time in hours after administration of the Investigational Veterinary Product (curative efficacy), or time in hours after flea infestation (preventative efficacy); h, hours