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Table 4 Summary of mortality amongst exposed and non-exposed T. infestans post-canine treatment bioassaysa

From: Systemic insecticide treatment of the canine reservoir of Trypanosoma cruzi induces high levels of lethality in Triatoma infestans, a principal vector of Chagas disease

Days post-canine treatment

Triatomines applied to treated dogs

Triatomines applied to control dogs

Proportion (dead/exposed)

Dead/Non-exposed

Dead/Exposed

Dead/Non-exposed

Bravecto®

 2

1 (42/42)

0/3

0/9

0/6

 7

1 (41/41)

1/4

0/14

0/1

 21

1 (43/43)

0/2

0/13

1/2

 34

1 (36/36)

1/9

0/14

0/1

 51

1 (40/40)

1/5

0/15

0/0

 Total

1 (202/202)

0.13 (3/23)

0.0 (0/65)

0.10 (1/10)

Comfortis®

 2

0.55 (16/29)

0/17

0/14

0/1

 7

0.63 (27/43)

1/4

0/9

0/6

 21

0.48 (19/40)

0/5

0/14

0/1

 34

0.36 (16/44)

0/2

0/14

0/1

 51

0.03 (1/38)

3/8

1/14

0/1

 Total

0.41 (79/194)

0.11 (4/36)

0.02 (1/65)

0.0 (0/10)

NexGard®

 2

0.97 (29/30)

1/17

0/4

0/11

 7

1 (32/32)

0/13

0/12

0/3

 21

0.95 (38/40)

0/5

0/15

0/0

 34

1 (39/39)

4/6

0/15

0/0

 51

1 (40/40)

0/5

0/15

0/0

 Total

0.98 (178/181)

0.11 (5/46)

0.0 (0/61)

0.0 (0/14)

 Total (3 treatments)

 

0.11 (12/105)

0.01 (1/191)

0.03 (1/34)

  1. aCumulative numbers dead by 120 h post-triatomine exposure/potential exposure