Fig. 5
From: Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13071-017-2282-6/MediaObjects/13071_2017_2282_Fig5_HTML.gif)
Pathway analysis of the differential metabolites during acute and chronic infection. Metabolite features with putative identification were analyzed using MetaboAnalyst for potential impact on metabolic pathways in the acute phase a and chronic phase b. Small P-value and large pathway impact factor indicate that the pathway is greatly influenced, such as arachidonic acid metabolism pathway, which was highly impacted during acute and chronic infection. c A schematic illustration of the arachidonic acid metabolism pathway during chronic infection. Red and black circles represent upregulated and unaltered metabolites, respectively. As shown, arachidonic acid (AA), leukotriene A4 (LTA4), 14,15-HETE, and 15-deoxy-Δ12,14-PGJ2 were upregulated