Skip to main content

Table 1 Distribution of pfcrt haplotypes in P. falciparum cases from different geographical regions. Total, number of samples successfully analyzed for pfcrt 72–76 and 220 allelic types, respective percent values in parentheses. Mutated amino acid is underlined

From: Return of chloroquine sensitivity to Africa? Surveillance of African Plasmodium falciparum chloroquine resistance through malaria imported to China

Area

Total

Amino acid locus

72–76

220

CVMNK

CVIET

CVMNK + CVIET

A

S

A + S

East Africa

 Madagascar

4 (1.4)

4 (100)

0 (0)

0 (0)

4 (100)

0 (0)

0 (0)

 Malawi

2 (0.7)

2 (100)

0 (0)

0 (0)

2 (100)

0 (0)

0 (0)

 Mozambique

12 (4.1)

12 (100)

0 (0)

0 (0)

12 (100)

0 (0)

0 (0)

 Tanzania

6 (2.0)

6 (100)

0 (0)

0 (0)

6 (100)

0 (0)

0 (0)

 Uganda

3 (1.0)

1 (33.3)

2 (66.7)

0 (0)

1 (33.3)

2 (66.7)

0 (0)

 Zambia

8 (2.7)

7 (87.5)

1 (12.5)

0 (0)

7 (87.5)

1 (12.5)

0 (0)

West Africa

 Côte d’Ivoire

4 (1.4)

2 (50.0)

2 (50.0)

0 (0)

2 (50.0)

1 (25.0)

1 (25.0)

 Ghana

20 (6.8)

17 (85.0)

2 (10.0)

1 (5.0)

17 (85.0)

2 (10.0)

1 (5.0)

 Guinea

7 (2.4)

3 (42.9)

4 (57.1)

0 (0)

3 (42.9)

4 (57.1)

0 (0)

 Liberia

14 (4.8)

1 (7.1)

13 (92.9)

0 (0)

1 (7.1)

12 (85.7)

1 (7.1)

 Nigeria

32 (10.9)

17 (53.1)

12 (37.5)

3 (9.4)

17 (53.1)

11 (34.4)

4 (12.5)

 Sierra Leone

9 (3.1)

3 (33.3)

4 (44.4)

2 (22.2)

3 (33.3)

4 (44.4)

2 (22.2)

 Togo

6 (2.0)

6 (100)

0 (0)

0 (0)

6 (100)

0 (0)

0 (0)

South Africa

 South Africa

5 (1.7)

4 (80.0)

1 (20.0)

0 (0)

5 (100)

0 (0)

0 (0)

North Africa

 South Sudan

6 (2.0)

4 (66.7)

2 (33.3)

0 (0)

4 (66.7)

2 (33.3)

0 (0)

 Sudan

9 (3.1)

7 (77.8)

2 (22.2)

0 (0)

7 (77.8)

2 (22.2)

0 (0)

Central Africa

 Cameroon

11 (3.7)

7 (63.6)

3 (27.3)

1 (9.1)

6 (54.5)

3 (27.3)

2 (18.2)

 Angola

42 (14.3)

22 (52.4)

17 (40.5)

3 (7.1)

21 (50.0)

17 (40.5)

4 (9.5)

 Chad

3 (1.0)

2 (66.7)

1 (33.3)

0 (0)

2 (66.7)

0 (0)

1 (33.3)

 Congo

20 (6.6)

4 (20.0)

12 (60.0)

4 (20.0)

4 (20.0)

12 (60.0)

4 (20.0)

 DR Congo

11 (3.7)

6 (54.6)

2 (18.2)

3 (27.3)

5 (45.5)

5 (27.3)

3 (27.3)

 Equatorial Guinea

47 (16.0)

32 (68.1)

13 (27.7)

2 (4.3)

32 (68.1)

10 (21.3)

5 (10.6)

 Gabon

11 (3.7)

2 (18.2)

7 (63.6)

2 (18.2)

2 (18.2)

7 (63.6)

2 (18.2)

Total

292 (100)

171 (58.6)

100 (34.2)

21 (7.2)

169 (57.9)

93 (31.8)

30 (10.3)