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Table 1 Distribution of pfcrt haplotypes in P. falciparum cases from different geographical regions. Total, number of samples successfully analyzed for pfcrt 72–76 and 220 allelic types, respective percent values in parentheses. Mutated amino acid is underlined

From: Return of chloroquine sensitivity to Africa? Surveillance of African Plasmodium falciparum chloroquine resistance through malaria imported to China

Area Total Amino acid locus
72–76 220
CVMNK CVIET CVMNK + CVIET A S A + S
East Africa
 Madagascar 4 (1.4) 4 (100) 0 (0) 0 (0) 4 (100) 0 (0) 0 (0)
 Malawi 2 (0.7) 2 (100) 0 (0) 0 (0) 2 (100) 0 (0) 0 (0)
 Mozambique 12 (4.1) 12 (100) 0 (0) 0 (0) 12 (100) 0 (0) 0 (0)
 Tanzania 6 (2.0) 6 (100) 0 (0) 0 (0) 6 (100) 0 (0) 0 (0)
 Uganda 3 (1.0) 1 (33.3) 2 (66.7) 0 (0) 1 (33.3) 2 (66.7) 0 (0)
 Zambia 8 (2.7) 7 (87.5) 1 (12.5) 0 (0) 7 (87.5) 1 (12.5) 0 (0)
West Africa
 Côte d’Ivoire 4 (1.4) 2 (50.0) 2 (50.0) 0 (0) 2 (50.0) 1 (25.0) 1 (25.0)
 Ghana 20 (6.8) 17 (85.0) 2 (10.0) 1 (5.0) 17 (85.0) 2 (10.0) 1 (5.0)
 Guinea 7 (2.4) 3 (42.9) 4 (57.1) 0 (0) 3 (42.9) 4 (57.1) 0 (0)
 Liberia 14 (4.8) 1 (7.1) 13 (92.9) 0 (0) 1 (7.1) 12 (85.7) 1 (7.1)
 Nigeria 32 (10.9) 17 (53.1) 12 (37.5) 3 (9.4) 17 (53.1) 11 (34.4) 4 (12.5)
 Sierra Leone 9 (3.1) 3 (33.3) 4 (44.4) 2 (22.2) 3 (33.3) 4 (44.4) 2 (22.2)
 Togo 6 (2.0) 6 (100) 0 (0) 0 (0) 6 (100) 0 (0) 0 (0)
South Africa
 South Africa 5 (1.7) 4 (80.0) 1 (20.0) 0 (0) 5 (100) 0 (0) 0 (0)
North Africa
 South Sudan 6 (2.0) 4 (66.7) 2 (33.3) 0 (0) 4 (66.7) 2 (33.3) 0 (0)
 Sudan 9 (3.1) 7 (77.8) 2 (22.2) 0 (0) 7 (77.8) 2 (22.2) 0 (0)
Central Africa
 Cameroon 11 (3.7) 7 (63.6) 3 (27.3) 1 (9.1) 6 (54.5) 3 (27.3) 2 (18.2)
 Angola 42 (14.3) 22 (52.4) 17 (40.5) 3 (7.1) 21 (50.0) 17 (40.5) 4 (9.5)
 Chad 3 (1.0) 2 (66.7) 1 (33.3) 0 (0) 2 (66.7) 0 (0) 1 (33.3)
 Congo 20 (6.6) 4 (20.0) 12 (60.0) 4 (20.0) 4 (20.0) 12 (60.0) 4 (20.0)
 DR Congo 11 (3.7) 6 (54.6) 2 (18.2) 3 (27.3) 5 (45.5) 5 (27.3) 3 (27.3)
 Equatorial Guinea 47 (16.0) 32 (68.1) 13 (27.7) 2 (4.3) 32 (68.1) 10 (21.3) 5 (10.6)
 Gabon 11 (3.7) 2 (18.2) 7 (63.6) 2 (18.2) 2 (18.2) 7 (63.6) 2 (18.2)
Total 292 (100) 171 (58.6) 100 (34.2) 21 (7.2) 169 (57.9) 93 (31.8) 30 (10.3)