Table 6 Proteins involved in endocytosis and intracellular transport identified in the midgut of Ornithodoros moubata females before feeding (unfed) and at 48 h post-feeding (fed). (T) Gene identified in the intestinal transcriptome of O. moubata [29]

Unfed

EST_Acari

G9F9U2

ABC C2 transporter

0.26

–

Transmembranne transport

Unfed

EST_Acari

B7PAI1

Acetylcholine regulator unc-18

1.47

–

Vesicular transport

Unfed

EST_Acari

A0A087U0D4

AP-1 complex subunit beta-1 (T)

0.7

–

Vesicular transport

Unfed

EST_Acari

A0A087TIH9

AP-1 complex subunit sigma-2 (T)

0.44

–

Vesicular transport

Unfed

EST_Acari

A0A087UKS9

AP-2 complex subunit alpha-2 (T)

0.26

–

Vesicular transport

Unfed

NCBI_metazoa

A0A087TIC9

Clathrin heavy chain 1 (T)

0.03

–

Vesicular transport

Unfed

EST_Acari

F0J8C0

Glucose derepression and pre-vacuolar endosome protein sorting protein

0.3

–

Vacuolar transport

Unfed

mRNA_Om

B7PRM4

VAMP-7 (T)

0.22

–

Endocytosis

Fed

mRNA_Om

Q7QHU5

AGAP011358-PA

–

0.26

Vesicular transport

Fed

mRNA_Om

B7PEY0

AP-2 complex subunit alpha-1 (T)

–

0.38

Vesicular transport

Fed

EST_Acari

Q6WCQ8

Beta-adaptin (T)

–

0.37

Vesicular transport

Fed

EST_Acari

V9TLV5

Clathrin (T)

–

0.37

Vesicular transport

Fed

mRNA_Om

Q8T9S5

Clathrin-adaptor protein (T)

–

0.2

Vesicular transport

Fed

NCBI_metazoa

A0A090L934

Coatomer subunit alpha (T)

–

0.23

Vesicular transport

Fed

EST_Acari

B7PXJ9

COPII vesicle protein

–

0.27

Vesicular transport

Fed

mRNA_Om

Q6QT18

KOG1656-like protein (T)

–

0.17

Vacuolar transport

Fed

EST_Acari

B7PMB5

Phosphatidylinositol-binding clathrin assembly protein (T)

–

0.23

Clathrin coat assembly

Fed

EST_acari

D6WJQ8

Rab-protein 5

–

0.76

Vesicular transport

Fed

mRNA_Om

B7PES3

Vesicle coat complex AP-3, delta subunit (T)

–

0.14

Vesicular transport

Fed

EST_Acari

F0J8Z5

Vesicle coat complex COPI beta’ subunit (T)

–

0.25

Vesicular transport

Fed

mRNA_Om

A0A087TZJ7

Vesicle transport through interaction with t-SNAREs-like protein 1B (T)

–

0.12

Vesicular transport

Fed

mRNA_Om

A0A087TTT4

Vesicle-associated membrane protein 1 (T)

–

0.09

Vesicular transport

Unfed-Fed

mRNA_Om

Q3YB24

ABC transporter ABCA1 (T)

0.07

0.04

Transmembranne transport

Unfed-Fed

mRNA_Om

B7PUI6

ABC transporter (T)

6.52

3.87

Transmembranne transport

Unfed-Fed

mRNA_Om

B7Q6V9

AP complex subunit beta (T)

0.48

0.45

Vesicular transport

Unfed-Fed

mRNA_Om

B7P454

Cargo transport protein EMP24 (T)

0.62

0.92

Protein transport

Unfed-Fed

mRNA_Om

B7PUK8

Clathrin heavy chain (T)

0.57

0.77

Vesicular transport

Unfed-Fed

mRNA_Om

A0A087U9S2

Coatomer subunit beta (T)

0.37

0.84

Vesicular transport

Unfed-Fed

mRNA_Om

A0A087UHC8

Coatomer subunit gamma-2 (T)

0.38

0.61

Vesicular transport

Unfed-Fed

mRNA_Om

B7PM12

Dynamin (T)

0.13

0.1

Clathrin-dependent endocytosis

Unfed-Fed

EST_Acari

B7P6P0

Glycoprotein 25 l

0.9

0.91

Protein transport

Unfed-Fed

EST_Acari

B7QNW0

Protein required for fusion of vesicles in vesicular transport, alpha-SNAP

0.46

0.49

Intracellular protein transport

Unfed-Fed

EST_Acari

Q6XP57

Rab11–2

1.87

1.4

Vesicular transport

Unfed-Fed

EST_Acari

B7QFX7

RAB-9 and, putative

3.64

3.67

Vesicular transport

Unfed-Fed

mRNA_Om

A0A087TXJ3

Rab GDP dissociation inhibitor beta (T)

2.33

1.51

Protein transport

Unfed-Fed

mRNA_Om

B7PAE0

RAS-related protein (T)

0.16

0.29

Regulation of endocytosis

Unfed-Fed

mRNA_Om

B7Q8P2

Sorting nexin (T)

0.15

0.44

Endocytosis

Unfed-Fed

mRNA_Om

B7PZR4

Surfeit 4 protein (T)

0.22

0.63

Vesicular transport

Unfed-Fed

EST_Acari

A0A023JCU7

Synaptobrevin (P)

0.18

0.28

Vesicular transport

Unfed-Fed

mRNA_Om

B7P427

Transmembrane protein Tmp21 (T)

2.0

1.74

Protein transport

Unfed-Fed

EST_Acari

B7P164

Vacuolar protein sorting-associated protein 29 (T)

0.52

0.46

Intracellular protein transport

Unfed-Fed

mRNA_Om

B7QLI1

Vacuolar sorting protein (T)

0.09

0.17

Intracellular protein transport

Unfed-Fed

EST_Acari

B7PDY5

Vesicle coat complex COPII, GTPase subunit SAR1 (T)

0.81

1.65

Vesicular transport