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Table 2 Characterisation of the secretory protein families in the R. zambeziensis transcriptome

From: Sialotranscriptomics of Rhipicephalus zambeziensis reveals intricate expression profiles of secretory proteins and suggests tight temporal transcriptional regulation during blood-feeding

Secretory protein family Number of family members Proportion of family members (%) Average TPMa value Sum of the family expression (TPMa) Proportion of family expression (%)
Lipocalin 588 22.90 39.88 23,452.37 5.62
Bovine pancreatic trypsin inhibitor 307 11.95 34.07 10,458.51 2.51
Reprolysin 213 8.29 19.36 4123.57 0.99
TIL domain 177 6.89 38.05 6735.14 1.61
Glycine rich superfamily 161 6.27 1842.35 296,618.84 71.07
Basic tail secreted protein 111 4.32 43.04 4777.46 1.14
8.9 kDa family 91 3.54 74.27 6758.57 1.62
Digestive system (including Serine proteases) 87 3.39 9.57 832.96 0.20
Mucin 62 2.41 47.14 2922.86 0.70
28 kDa Metastriate family 56 2.18 31.67 1773.45 0.42
Evasin 55 2.14 33.33 1832.92 0.44
Secretory - unknown function 46 1.79 455.62 20,958.56 5.02
Folding, sorting and degradation (including Cathepsins) 46 1.79 88.22 4058.19 0.97
Cystatin 45 1.75 17.27 777.09 0.19
Gluzincin 43 1.67 7.34 315.45 0.08
Serpin 33 1.29 6.30 207.96 0.05
Ixodegrin B 32 1.25 55.31 1770.02 0.42
One of each family 28 1.09 3.71 103.68 0.02
Carboxypeptidase inhibitor 27 1.05 16.01 432.37 0.10
Chitin-binding proteins 26 1.01 20.30 527.89 0.13
5′-Nucleotidase 25 0.97 6.56 163.87 0.04
Transport and catabolism 24 0.93 35.23 845.47 0.20
24 kDa family 21 0.82 24.99 524.87 0.13
7 dB family 19 0.74 11.34 215.53 0.05
DA-P36 family 19 0.74 10.15 192.90 0.05
Defensin 19 0.74 211.69 4022.20 0.96
ML domain 17 0.66 417.39 7095.58 1.70
Antigen 5 family 14 0.55 57.55 805.64 0.19
Microplusin 14 0.55 47.61 666.59 0.16
8 kDa Amblyomma family 13 0.51 24.52 318.79 0.08
Sphingomyelinase 11 0.43 2.93 32.22 0.01
Glycan biosynthesis and metabolism 10 0.39 9.36 93.63 0.02
Lipid metabolism 10 0.39 5.88 58.76 0.01
Transcription 10 0.39 3.75 37.52 0.01
Translation 8 0.31 10.62 84.92 0.02
Serine/threonine protein kinase 8 0.31 6.59 52.70 0.01
Carbohydrate metabolism 8 0.31 3.53 28.21 0.01
Thyropin 7 0.27 22.67 158.66 0.04
Fibrinogen-related domain 7 0.27 20.84 145.85 0.03
Glutathione metabolism 7 0.27 16.63 116.41 0.03
Metalloprotease 7 0.27 8.28 57.93 0.01
Dermacentor 9 kDa expansion 6 0.23 11.81 70.86 0.02
Replication and repair 6 0.23 5.56 33.37 0.01
Immunoglobulin G binding protein A 5 0.19 989.88 4949.38 1.19
Phospholipase A2 5 0.19 9.54 47.69 0.01
Kazal/vWf domain 4 0.16 4.78 19.11 0.005
Hirudin 3 0.12 108.72 326.17 0.08
SALP15/Ixostatin 3 0.12 35.45 106.35 0.03
14 kDa family 3 0.12 9.75 29.25 0.01
Kazal domain 3 0.12 9.28 27.85 0.01
Signal transduction 3 0.12 2.23 6.68 0.002
Madanin 2 0.08 153.53 307.05 0.07
Energy metabolism 2 0.08 13.13 26.25 0.01
CDIV 2 0.08 9.44 18.88 0.005
EF hand domain 2 0.08 5.33 10.65 0.003
Histamine release factor 1 0.04 6057.33 6057.33 1.45
Fatty acid-binding protein 1 0.04 70.19 70.19 0.02
Kazal/SPARC domain 1 0.04 70.11 70.11 0.02
Immune system 1 0.04 21.85 21.85 0.01
Cysteine rich hydrophobic domain 2 1 0.04 10.83 10.83 0.003
26 kDa family 1 0.04 5.49 5.49 0.001
Proline rich 1 0.04 5.09 5.09 0.001
Cysteine rich 1 0.04 2.23 2.23 0.001
  1. aTPM (transcripts per million) values were used to estimate expression