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Table 1 Mean lice counts and efficacy (%) after a single oral administration of fluralaner or topical administration of permethrin to dogs naturally infested with lice L. setosus

From: Efficacy of fluralaner (Bravecto™ chewable tablets) for the treatment of naturally acquired Linognathus setosus infestations on dogs

  Study day Dogsa Count range (n) Geometric mean lice count Efficacy (%) P-valuec
Fluralaner 0 14 1–115 8.0
1 14 0–38 1.6 85.7 0.0088
7 14 0–3 0.3 96.8 < 0.0001
28 13 0–0 0.0 100 < 0.0001
84 11 0–0 0.0 100 < 0.0001
Permethrin 0 10 1–36 10.2
1 10 0–25 3.3 67.5 0.0854
7 9b 0–7 1.0 90.3 0.0014
28 8b 0–1 0.1 99.1 < 0.0001
  1. aNumber of dogs presented to visit
  2. bDog withdrawn from the study due to insufficient permethrin treatment effect against L. setosus
  3. cTwo-sided two-sample t-test (α = 0.05)