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Table 2 Lice-free dogs and households after a single oral administration of fluralaner or topical administration of permethrin to dogs naturally infested with lice L. setosus

From: Efficacy of fluralaner (Bravecto™ chewable tablets) for the treatment of naturally acquired Linognathus setosus infestations on dogs

Study day Lice-free dogs Lice-free households
Fluralaner (%) Permethrin (%) Lower 97.5% CLa P-valueb Fluralaner (%) Permethrin (%) Lower 97.5% CLa P-valueb
1 64 20.0 0.0417 0.0019 62 13 0.0554 0.0020
7 79 44.4 -0.0502 0.0070 77 43 -0.0858 0.0121
28 100 87.5 -0.1311 0.0177 100 83 -0.1182 0.0147
84 100 na 100 na
  1. Abbreviation: na not applicable
  2. aConfidence limits based upon the Farrington-Manning test of non-inferiority for the risk difference. Results > -0.15 for significant non-inferiority and results > 0 for significant one-sided superiority with α = 0.025
  3. bFarrington-Manning test of non-inferiority for the risk difference