Table 1 Comparison of T. bryosalmonae numbers in immunohistochemical stained tissues and histopathological lesion scores in different groups. Presented data are the mean values of T. bryosalmonae numbers from immunohistochemical stained tissues and the results of histopathological lesion scores from kidneys samples at 60, 90 and 120 dpe

 1-Interstitium

43.71 ± 21.17 (20–74)^b

39.5 ± 21.67 (24–87)^b

99.4 ± 43.24 (45–164)^a

58.71 ± 30.17 (18–94)^b

68.6 ± 12.09 (55–82)^b

156.0 ± 36.03 (98–192)^a

90.83 ± 21.79 (68–120)^a

121.67 ± 14.57 (110–138)^a

 2-Blood vessels

0.71 ± 1.25 (0–3)^a

5.00 ± 10.62 (0–31)^a

5.2 ± 4.15 (0–11)^a

2.86 ± 1.86 (0–5)^b

2.8 ± 1.92 (0–5)^b

8.0 ± 4.0 (2–12)^a

3.83 ± 1.83 (2–7)^a

3.33 ± 1.53 (2–5)^a

 3-Interepithelial

0.43 ± 0.79 (0–2)^a

0.5 ± 1.07 (0–3)^a

0.6 ± 0.89 (0–2)^a

0.0 (0–0)^b

0.0 (0–0)^b

2.2 ± 1.3 (0–3)^a

0.0 (0–0)^a

0.0 (0–0)^a

  1-Infiltration of inflammatory cells

3 (2–4)

3 (2–5)

4 (3–5)

4 (4–5)

5 (4–5)

6 (4–6)

5 (5–6)

6 (5–6)

  2-Fibosis

3 (2–5)

3 (2–5)

4 (3–5)

4 (4–5)

4 (3–5)

6 (4–6)

5 (4–6)

6 (5–6)

  3-Haemorrhage

1 (1–2)

3 (2–4)

4 (3–5)

3 (3–4)

4 (4–5)

3 (2–3)

2 (2–3)

2 (2–3)

  4-Parasites with daughter cells

3 (2–5)

3 (2–4)

4 (4–5)

4 (3–5)

4 (4–5)

5 (4–6)

5 (4–6)

5 (5–6)

  1-Thrombi

1 (1–2)

2 (1–3)

3 (2–3)

2 (1–4)

3 (2–3)

3 (2–4)

3 (2–4)

2 (2–3)

  2-Parasites

1 (1–2)

1 (0–4)

2 (0–2)

1 (0–2)

1 (0–2)

2 (1–2)

1 (1–2)

1 (1–2)

  1-Tubulonephrosis & necrosis

3 (2–4)

3 (3–4)

3 (2–4)

2 (1–2)

2 (2–3)

3 (2–3)

0 (0–1)

0 (0–1)

  2-Nephron neogenesis

1 (1–2)

1 (0–1)

2 (1–3)

3 (2–4)

3 (2–4)

4 (4–5)

5 (5–6)

5 (5–6)

  3-Intraluminal stages of parasite

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)