Table 2 Performance of each antigen in ELISA when including only known-infected vs known-uninfected dogs. True positive sera (n = 14 of group 1) were analysed against true negative sera (group 3) only. This scenario represents an ideal but unrealistic situation with a clear differentiation between positive and negative animals
From: Dogs as victims of their own worms: Serodiagnosis of canine alveolar echinococcosis
ELISA | AUC | Cut-off | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|---|
recEm95 | 1 | 0.261 | 1 (0.72–1) | 1 (0.83–1) |
Em2 | 0.821 | 0.430 | 0.79 (0.52–0.92) | 0.95 (0.76–0.99) |
EmVF | 1 | 0.574 | 1 (0.78–1) | 1 (0.84–1) |
recEm18 | 0.932 | 0.268 | 0.86 (0.60–0.96) | 1 (0.84–1) |